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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fe0de65dc813e1b702efaa11cdbf6346200379ec6bf3a51e9996afbc2be08c2' 
  AND token = 'CglYSl21FFT0TA2l/fOEe8X3SpCk6ngz4N3F2oDG7TE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}