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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0ab0bbc2ade1eeff85bdf1e1fb99c05f69e987c44268e199c9b7123c04e3206' 
  AND token = 'wrsGyvyJlsYa1W2D4zO4R7BpPOO4OGy9/5Typyl1ZGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}