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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2961594b54d3e7aae1b5f6b394684a258a3ac912b8aa990553ca9f8c151717ac' 
  AND token = 'vUxhqM4SF85Akr0UAMbHd7Rl4DMlJO1ZfLs1vUFObcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}