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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c8a3e0af4c46b27cbfc2c4e1b18b81ae64cd32734df0f209cfcbfddac405e80' 
  AND token = '+xSXCElgzySIWDLBb6yjxSVk08NY+11sr4HuQ7B0dBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}