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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63da9bdcd8cfa40647e31fcdd69e398aac7468fdfeb0562347dbd8b5417c7b54' 
  AND token = 'YEL3FIONZH+c37rtKj4nRQI4bRPrMt6LHJ2BS1QOQBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}