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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5af1e2c2df664ec92df41350afbb5152f62ca2c9a27594a22e03c63dd20fd9f5' 
  AND token = 'Sy0jjyxUnfAJvo5kASn0EGWqrNh3/efH1SOy/yDTwgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}