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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5db11eaf350e30d0480f9c8906aad5f951499d5bd028defd632e0cafc39a789a' 
  AND token = 'MZ2EQiQQjl4S3qPjQOdE7hW8eh7i8dqfSCKUpU3IVu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}