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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '601e7c96703fbb7826883bfc4564ffda698bab8efaa20b5e1b2b38eaa39ea444' 
  AND token = '5eMvCqFWeRcaoCBDfHcOKZEP8L0LADCXQfVPE3O4YA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}