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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f2cd1f1abf38e642d21900081e5ba6cf1bfcb641c9ea763f35038a86408a64f' 
  AND token = 'ULaxzxgP8qnJCXva5nExezfRx605qovMewfSKAfw0vg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}