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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '232f271c463d7511b4fa3849baec0659646bf63e83382a563a670369d21aa58a' 
  AND token = 'AX8F+f9AIQ0vJ+bmqe7wGGDJOvWiimYNM0iiuCvFmsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}