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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c901cff95ea4e238b47338c70dca33853591a694860dc36295f9f1b4c3d4b3a' 
  AND token = 'LyeV+2xS1F1hviWelzgoipVMk+g6jc0edKkQWpmIfhw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}