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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5bfea7b8f317aaae06c4282c22bdf0fa417f2b444a4408642749fcd4c998cd1' 
  AND token = 'ZBBsKAF8v4ymmOO2hemBawTLFhQEIy1F7HSkz2w0mlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}