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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eed7c203d9dd284e64f1776d6a83a3a9ed403b73e0d0c4fbf9a4e02a887d2112' 
  AND token = 'R7gzExwMoeQ3msqfRrZLuENmgw3wMT6CRY8vUJAdO10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}