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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce860198c78710fc4ab7c0328f4a3ef4070b8d58e4507d242e5821cd9f6f1c15' 
  AND token = 'EYFQh2djpNe71Ps78aQqVHjTf3hfypKbm2CfCKDtEdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}