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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1197983cdc792d09845470e06bba518dbfc850fed8f1218f7cfb318edee06709' 
  AND token = 'vKJBkzGke3vvl6d3SSn4Jv1iz1PDS+e4Ej7WTHhZReI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}