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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1222336543c93d20a6d625452d3e8790acce4957623b03ee4dd7e4375b0313d8' 
  AND token = 'mL76QhgTLTDT90aL+WL5overucFdNprC+D7uXHgb7e4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}