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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25567c0a7550ad1e14e91f0e21db1c35156bd6dbc80b57da911a04bab65da6e3' 
  AND token = 'UbRIeIbbro4Kr85vG/YcMvsKSIB6IdL1238+caHJ18o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}