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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e85a125346bad65ea3aa67a162ddc9a1adbc9d9699b157be4fc279617db858da' 
  AND token = 'tD/RpoCUovOh11bsrmJxZ+npmy8c0AlmN386gKAz6Wo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}