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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b7a40e56be7265047d6159b152d821e0f659675096ef27c0371de2d50805a11' 
  AND token = 'NJuLyEC3MupupAaBzRsspYUgbftuXoU75VF7GLZk4S0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}