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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44ca39a40a0a2e1b00071ed41bebb01e58726e47c7979da19b6409b58a44534c' 
  AND token = 'Vly0zw1ivAY1XfaESa2UHbuMKJVW3XlPAW9a6xpryvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}