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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3d44422c007c18600dbb09552c50ba0ce56e8aaa4aeb16d74596fa8fe5f43a7' 
  AND token = 'jd/V30U1O53wRFgDlgv6k/SyGFfrF3QtpPla+EH/shw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}