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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb4c290610d92ba11e489074d2f4bb4b0e83bbf5491a67df8de7c8599c56a9b2' 
  AND token = '2SSTntHWVPGt72gaaTxXjuy8FcZkJOad6nYj5ncEMFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}