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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ed5eb4f67796cdf1870250d0d6e55c09a5f10e9f1d80c0501245ab864dd4196' 
  AND token = '72VJCcJGJRfNZDdopQI/dNlBz5mQSJ3LLi4+VS6bn2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}