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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b43c17a32a5e954fd77016c7537a6d050e66130250c7cd725e3772bc097838a' 
  AND token = 'Xx6XSQiQmr5qz/zR1L1vUwNK4i7nQ0xUYlI3grzRVsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}