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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a060494f88bb4b1b7651d3d392a728b0c0e3c9191033953faac90245b703e9b7' 
  AND token = 'ftEgSc4m1VovrMhUTJIWDN8hbDnsS2xt7FMyGzw8aMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}