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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27369fae9f5b7a032bfe0f798ca2ebb0b2527cbcc885ba1130e585e6b4fd9027' 
  AND token = 'ip1yP17k9gyWq4bm20YjXR9qNmz67xPP4v1cqkbYKJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}