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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f37789b8330f0bdd452e3a82c4e7941ce45b9bd6f9e4d9490428ee8451a5c8dd' 
  AND token = 'vc28N1Z/JeBFmDP42K7koN1iqQPda2rv66MZhD8IuMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}