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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '887c8e8e4b1ab9e52c0b15db0dd66337752c9141e3a09cffa7141e56f04c1e1f' 
  AND token = 'uPEUAN4s+fuDtoNKJTqICez/cvIYDQeDo5PGmxCTtmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}