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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9e31bb214a42869d8516ba44c7c4021b162475e412206666a21e8ffdaff2518' 
  AND token = 'ODVMo613+5+gvI3IojysIoKam5Da4NElS7WSaln8qaw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}