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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cb0159414b3697a8af5effdb0337c505bd99af89febd475d60db6493f354e89' 
  AND token = 'EmWtkL2T/vrVdIMPaUq9AZ3FRv/zXwb8wv7ur2CVr0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}