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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bd7346011ffcddc36760328463bc4b38b02a32e5d9a145be402e109e1f7434a' 
  AND token = 'uKpxXNYhh4nCEF+gRJ4kZyg3Ar6noqKXttKUskZ5WR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}