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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bbe4d61ba8d5306dff86c97ae724c36a0ce0d7ed2e8e21940472a82b3dd8c05' 
  AND token = 'ypBYVL7Y73f4tP+dBBxS8CZ9cCKq6uDl9tM0e48PPn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}