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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41d5567be2f176e3e9fca568e4627534b7b914ab7bd568ae47711db5b2a49918' 
  AND token = 'DrR60kkHyvW2bqkDINDM9LB9JJbfUczbJfPIOOQPyJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}