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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f324271c94b6045103e78263726f7454cc60539e9fc0430309b59ec38b9f31a3' 
  AND token = 'RjS5ikVQMCh5AgYJDj79vtp6vp2TVk3cQMsDBFgbh+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}