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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27cdd6b0a60f8cab8febac7697803490a52f065abf58e5ac81c548bae86d864c' 
  AND token = 'eRUAwdgn8xRK2U3tKBMS/autaPRYcvPEfmkBp43FLYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}