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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '727cb87a646c54431c2fcea51c0ca81068af9405bfa769f017272c89df6182ca' 
  AND token = 'z9mCyqpRiRFohwwHpryGkbh2hdwLPFh67ldWP/9qRAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}