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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '208c09dba6d96605811e2df1bdf5fe7f21272bdfe6ba00531b860c0135e1ea9f' 
  AND token = 'JdUAkfK7YNh2eVCG9Xs6ea3+Wtdnm4CusB5T4TUsFOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}