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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a80aaf131795f6095f1f232a82c94f02f562420042277c227f9a0bbdf0c50f9' 
  AND token = 'DBVt11yYBPlU50eI4O4J0c2Z8p2fjVm0u7TO2BeobFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}