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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '288e0017d71a5223c5a60956382aaf75d6e7beea2e8982f8411c47a7b03809f1' 
  AND token = 'leWXtfWItkzPq7VDoWeK457vlWdx0bpzpTeq7d2n8mQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}