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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7c5cfb216e10a08464b36a11e7f6e07b6183f3c98cbcd437b031da129d39343' 
  AND token = 'isXBaAWUaIR+ERWyUFrXN3vvL7c6PxfNz38u2E3mYU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}