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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b50b7317beadd1654d96a5139ac96494d0f323f3c2c24b566f469535fd83d8f4' 
  AND token = 'jE4SrYPQ0xmaAAyrqq3MO00WAj7fZN1SJUGXsA/SwPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}