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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e751b9de2ecb5022aa52b602823b09e77f80893f1233611ffbad61a27916bcd1' 
  AND token = 'ZGV4AjwLUg3GTdbFq4XOVAT05kUA2EaLI6tk2VUqbPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}