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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9261d3410bb0d8f43269efb1e9e2f759cbc96b96cf6800072f24b7fd8d726358' 
  AND token = 'bomOjIHinYrpE5E2kCEWq534d4XnV1OEOmLrlCUHNAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}