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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71e48d3aeb438604f2e6cf8a58fb7ba7a42394f77b0973ed0cfe5aca8effd260' 
  AND token = '74ngOkaMW42RdyDt9iutOAL8dnFqSpepgh381f9jvWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}