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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5429cab39878fc355935f64b915255838307843b0af5cb9bd6947f59be60c715' 
  AND token = 'lK/uiVeFWBnk5MGVsbIJE4s+DWo6aibeFj122Y+aS0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}