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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a2e13163b5642e753b89c472ba710cde8bc8385264abe7a48cd3e7bceaad3ed' 
  AND token = '4F3bZOxbO+c3FOBu4wv6OwAe8KroGHxgxBmxwS43xbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}