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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2ea6c0b1bc42cac13eff5a53609fb467b30dc756ac0d1c1df55990d960d4521' 
  AND token = 't87UEA6vuH6DDb01mYr7rEpjZV9ytVaeYNxDfwADE44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}