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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdc7c7f7694d8984bcb73b47512ef0ffb512a952c6713d69bf812461f7b04845' 
  AND token = 'I7FQx9UnZb/Us9x/Hr2S5iMQu7wb81+Wqk/t6Ih/JMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}