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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9acd9390cfe30de4cc11817e626bfc46b9dbb4d66aa50a893542a78dbe7c26a7' 
  AND token = 'mbQMXIbotm/gW3yr2BK08IOxClzTfP9QUrXxRxfv53A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}