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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa1790226e27b8979a2a82f2490df899c40f2d8515b809d9c3e97a12789f4963' 
  AND token = '8KmMmMhheXMU+jVA2it0j9y/w+kHbaAjzZS4qNVs0T0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}